Snapshots of Fluoride Binding in an Aza Cryptand
Thirty years after the first observation of halide encapsulation by katapinand receptors, the authors have utilized {sup 19}F NMR spectroscopy in conjunction with X-ray crystallography to provide snapshots of fluoride binding in an aza cryptand, 1, over a range of pH values. The results provide defi...
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Published in | Journal of the American Chemical Society Vol. 122; no. 8; pp. 1814 - 1815 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
American Chemical Society
01.03.2000
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Subjects | |
Online Access | Get full text |
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Summary: | Thirty years after the first observation of halide encapsulation by katapinand receptors, the authors have utilized {sup 19}F NMR spectroscopy in conjunction with X-ray crystallography to provide snapshots of fluoride binding in an aza cryptand, 1, over a range of pH values. The results provide definitive solution and solid-state evidence for the incorporation of fluoride in the cavity. This is the first study that integrates crystallographic findings with {sup 19}F NMR data as a means of understanding the binding patterns of fluoride as a function of pH. |
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Bibliography: | ark:/67375/TPS-CR5VRCMW-7 istex:70975A234EAFD43E46B3C9D38989E54B697B8B3F USDOE FG07-96ER62307 |
ISSN: | 0002-7863 1520-5126 |
DOI: | 10.1021/ja9939800 |