Hypochlorous Acid Turn-on Fluorescent Probe Based on Oxidation of Diphenyl Selenide
A BODIPY-based fluorescent probe, HCSe, has been successfully developed for the rapid detection of hypochlorous acid based on the specific HOCl-promoted oxidation of diphenyl selenide in response to the amount of HOCl. Confocal fluorescence microscopy imaging using RAW264.7 cells showed that the new...
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| Published in | Organic letters Vol. 15; no. 4; pp. 878 - 881 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
WASHINGTON
American Chemical Society
15.02.2013
Amer Chemical Soc |
| Subjects | |
| Online Access | Get full text |
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| Abstract | A BODIPY-based fluorescent probe, HCSe, has been successfully developed for the rapid detection of hypochlorous acid based on the specific HOCl-promoted oxidation of diphenyl selenide in response to the amount of HOCl. Confocal fluorescence microscopy imaging using RAW264.7 cells showed that the new probe HCSe could be used as an effective fluorescent probe for detecting HOCl in living cells. |
|---|---|
| AbstractList | A BODIPY-based fluorescent probe, HCSe, has been successfully developed for the rapid detection of hypochlorous acid based on the specific HOCl-promoted oxidation of diphenyl selenide in response to the amount of HOCl. Confocal fluorescence microscopy imaging using RAW264.7 cells showed that the new probe HCSe could be used as an effective fluorescent probe for detecting HOCl in living cells. |
| Author | Liu, Shi-Rong Wu, Shu-Pao |
| AuthorAffiliation | National Chiao Tung University |
| AuthorAffiliation_xml | – name: National Chiao Tung University |
| Author_xml | – sequence: 1 givenname: Shi-Rong surname: Liu fullname: Liu, Shi-Rong – sequence: 2 givenname: Shu-Pao surname: Wu fullname: Wu, Shu-Pao email: spwu@mail.nctu.edu.tw |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23373559$$D View this record in MEDLINE/PubMed |
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| Snippet | A BODIPY-based fluorescent probe, HCSe, has been successfully developed for the rapid detection of hypochlorous acid based on the specific HOCl-promoted... |
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| SubjectTerms | Animals Biphenyl Compounds - chemistry Boron Compounds - chemical synthesis Boron Compounds - chemistry Chemistry Chemistry, Organic Fluorescent Dyes - chemical synthesis Fluorescent Dyes - chemistry Hypochlorous Acid - analysis Hypochlorous Acid - chemistry Macrophages - drug effects Mice Molecular Structure Organoselenium Compounds - chemical synthesis Organoselenium Compounds - chemistry Oxidation-Reduction Physical Sciences Science & Technology |
| Title | Hypochlorous Acid Turn-on Fluorescent Probe Based on Oxidation of Diphenyl Selenide |
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