Hypochlorous Acid Turn-on Fluorescent Probe Based on Oxidation of Diphenyl Selenide

A BODIPY-based fluorescent probe, HCSe, has been successfully developed for the rapid detection of hypochlorous acid based on the specific HOCl-promoted oxidation of diphenyl selenide in response to the amount of HOCl. Confocal fluorescence microscopy imaging using RAW264.7 cells showed that the new...

Full description

Saved in:
Bibliographic Details
Published inOrganic letters Vol. 15; no. 4; pp. 878 - 881
Main Authors Liu, Shi-Rong, Wu, Shu-Pao
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 15.02.2013
Amer Chemical Soc
Subjects
Animals
Biphenyl Compounds - chemistry
Boron Compounds - chemical synthesis
Boron Compounds - chemistry
Chemistry
Chemistry, Organic
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Hypochlorous Acid - analysis
Hypochlorous Acid - chemistry
Macrophages - drug effects
Mice
Molecular Structure
Organoselenium Compounds - chemical synthesis
Organoselenium Compounds - chemistry
Oxidation-Reduction
Physical Sciences
Science & Technology
MYELOPEROXIDASE
Online AccessGet full text

Cover

More Information
Summary:A BODIPY-based fluorescent probe, HCSe, has been successfully developed for the rapid detection of hypochlorous acid based on the specific HOCl-promoted oxidation of diphenyl selenide in response to the amount of HOCl. Confocal fluorescence microscopy imaging using RAW264.7 cells showed that the new probe HCSe could be used as an effective fluorescent probe for detecting HOCl in living cells.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1523-7060
1523-7052
DOI:10.1021/ol400011u