Design of a “Turn-Off/Turn-On” Biosensor: Understanding Carbohydrate-Lectin Interactions for Use in Noncovalent Drug Delivery

A low-cost and highly sensitive biosensor system is designed to investigate carbohydrate-lectin interactions. This combination of glyco-gold nanoparticles and boronic acid biosensor system opens a way to study noncovalent drug delivery.

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Bibliographic Details
Published inJournal of the American Chemical Society Vol. 134; no. 37; pp. 15229 - 15232
Main Authors Gorityala, Bala Kishan, Lu, Zhiqiang, Leow, Min Li, Ma, Jimei, Liu, Xue-Wei
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 19.09.2012
Subjects
Biosensing Techniques
Carbohydrates - chemistry
Drug Delivery Systems
Lectins - chemistry
Nanoparticles
Spectrometry, Fluorescence
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Summary:A low-cost and highly sensitive biosensor system is designed to investigate carbohydrate-lectin interactions. This combination of glyco-gold nanoparticles and boronic acid biosensor system opens a way to study noncovalent drug delivery.
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ISSN:0002-7863
1520-5126
DOI:10.1021/ja306288p