Rhodium-Catalyzed Asymmetric Coupling Reaction of Allylic Ethers with Arylboronic Acids

An asymmetric allylic substitution of simple allylic ethers with arylboronic acids in the presence of a rhodium(I)/(R)-DTBM-SEGPHOS catalyst has been developed. The reactions proceeded smoothly at room temperature to give the corresponding branch products with excellent regioselectivities and good t...

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Bibliographic Details
Published inOrganic letters Vol. 14; no. 17; pp. 4502 - 4505
Main Authors Kiuchi, Hiroyoshi, Takahashi, Dai, Funaki, Kenji, Sato, Tetsuo, Oi, Shuichi
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 07.09.2012
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
ALCOHOLS
ACETATES
ORGANOBORONIC ACIDS
ARYL
1,4-ADDITION
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Summary:An asymmetric allylic substitution of simple allylic ethers with arylboronic acids in the presence of a rhodium(I)/(R)-DTBM-SEGPHOS catalyst has been developed. The reactions proceeded smoothly at room temperature to give the corresponding branch products with excellent regioselectivities and good to excellent enantioselectivities.
Bibliography:KAKEN
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1523-7060
1523-7052
DOI:10.1021/ol3019902