New Sensitive Fluorophores for Selective DNA Detection

4,7-Disubstituted benzothiadiazoles containing 1-arylethynyl and 4-methoxyphenyl groups are selective photoluminescent “light up” probes to duplex DNA with unprecedented sensibility in both spectrophotometric and spectrofluorimetric measurements.

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Bibliographic Details
Published inOrganic letters Vol. 9; no. 20; pp. 4001 - 4004
Main Authors Neto, Brenno A. D, Lapis, Alexandre A. M, Mancilha, Fabiana S, Vasconcelos, Igor B, Thum, Caroline, Basso, Luiz A, Santos, Diógenes S, Dupont, Jaïrton
Format Journal Article
LanguageEnglish
Published United States American Chemical Society 27.09.2007
Subjects
DNA - analysis
DNA - chemistry
Fluorescent Dyes - analysis
Fluorescent Dyes - chemistry
Molecular Structure
Sensitivity and Specificity
Spectrophotometry
Titrimetry
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Summary:4,7-Disubstituted benzothiadiazoles containing 1-arylethynyl and 4-methoxyphenyl groups are selective photoluminescent “light up” probes to duplex DNA with unprecedented sensibility in both spectrophotometric and spectrofluorimetric measurements.
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ISSN:1523-7060
1523-7052
DOI:10.1021/ol701708y