Thermal Cyclization of (2-Ethynylphenyl)triazenes:  Facile Synthesis of Substituted Cinnolines and Isoindazoles

High-temperature intramolecular cyclization of N,N-dialkyl-N ‘-(4-substituted-2-ethynylphenyl)triazenes provides under neutral conditions both 6-substituted cinnolines and 5-substituted isoindazoles in moderate to excellent yields.

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Bibliographic Details
Published inOrganic letters Vol. 2; no. 24; pp. 3825 - 3827
Main Authors Kimball, David B, Hayes, Austin G, Haley, Michael M
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 30.11.2000
Amer Chemical Soc
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Summary:High-temperature intramolecular cyclization of N,N-dialkyl-N ‘-(4-substituted-2-ethynylphenyl)triazenes provides under neutral conditions both 6-substituted cinnolines and 5-substituted isoindazoles in moderate to excellent yields.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1523-7060
1523-7052
DOI:10.1021/ol006517x