Intramolecular Hydroamination of Aminoalkynes with Silver−Phenanthroline Catalysts

Intramolecular hydroamination of several aminoalkynes catalyzed by silver−phenanthroline complexes is reported. This catalyst system complements previous protocols by employing air- and moisture-stable complexes without compromising activity or reaction control. Some of the hydroamination products a...

Full description

Saved in:
Bibliographic Details
Published inOrganic letters Vol. 10; no. 17; pp. 3903 - 3906
Main Authors Carney, Jeffrey M, Donoghue, Patrick J, Wuest, William M, Wiest, Olaf, Helquist, Paul
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 04.09.2008
Amer Chemical Soc
Subjects
Alkynes - chemistry
Amination
Amines - chemistry
Catalysis
Chemistry
Chemistry, Organic
Imines - chemical synthesis
Phenanthrolines - chemistry
Physical Sciences
Science & Technology
Silver - chemistry
Stereoisomerism
AMINATION
ENANTIOSELECTIVE SYNTHESIS
LIGANDS
INTERMOLECULAR HYDROAMINATION
ASYMMETRIC HYDROAMINATION
HYDROALKOXYLATION
COMPLEXES
ALKYNES
DERIVATIVES
CYCLIZATION
Online AccessGet full text

Cover

More Information
Summary:Intramolecular hydroamination of several aminoalkynes catalyzed by silver−phenanthroline complexes is reported. This catalyst system complements previous protocols by employing air- and moisture-stable complexes without compromising activity or reaction control. Some of the hydroamination products are subject to a useful aerobic oxidation. Silver−phenanthroline complexes have successfully demonstrated efficacy in the desymmetrization of a prochiral diyne.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1523-7060
1523-7052
1523-7052
DOI:10.1021/ol801458g