Lithium chloride perturbation of cis-trans peptide bond equilibria: effect on conformational equilibria in cyclosporin A and on time-dependent inhibition of cyclophilin

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Bibliographic Details
Published inJournal of the American Chemical Society Vol. 114; no. 7; pp. 2670 - 2675
Main Authors Kofron, James L, Kuzmic, Petr, Kishore, Vimal, Gemmecker, Gerd, Fesik, Stephen W, Rich, Daniel H
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 01.03.1992
Subjects
Biological and medical sciences
Immunomodulators
Medical sciences
Pharmacology. Drug treatments
Enzyme
Molecular interaction
Lithium Chlorides
Kinetics
Immunosuppressive agent
Mechanism of action
Conformational equilibrium
Structure function relationship
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Bibliography:istex:1BAB113C0EC7663AE75922652667B675186A381C
ark:/67375/TPS-M01L0G5L-X
ISSN:0002-7863
1520-5126
DOI:10.1021/ja00033a047