Restless Legs Syndrome is Associated with DSM-IV Major Depressive Disorder and Panic Disorder in the Community

The authors examined the association between restless legs syndrome (RLS) and DSM-IV major depressive disorder and panic disorder based on Wave III and IV of the Baltimore ECA follow-up study. Of 1071 participants, 1024 completed the RLS Questionnaire and Diagnostic Interview Schedule. Adjusted odds...

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Published inThe journal of neuropsychiatry and clinical neurosciences Vol. 20; no. 1; pp. 101 - 105
Main Authors Lee, Hochang B, Hening, Wayne A, Allen, Richard P, Kalaydjian, Amanda E, Earley, Christopher J, Eaton, William W, Lyketsos, Constantine G
Format Journal Article
LanguageEnglish
Published Washington, DC American Psychiatric Publishing, Inc 01.01.2008
American Psychiatric Press
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Summary:The authors examined the association between restless legs syndrome (RLS) and DSM-IV major depressive disorder and panic disorder based on Wave III and IV of the Baltimore ECA follow-up study. Of 1071 participants, 1024 completed the RLS Questionnaire and Diagnostic Interview Schedule. Adjusted odds ratio for diagnosis of major depressive disorder (4.7, 95% confidence interval [1.6, 14.5]) and panic disorder (12.9 [3.6, 46.0]) and comorbidity of major depressive disorder and panic disorder (9.7 [1.4, 69.0]) in the past 12 months suggested a strong association between restless legs syndrome and major depressive disorder and/or panic disorder.
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ISSN:0895-0172
1545-7222
DOI:10.1176/jnp.2008.20.1.101