Tracking Peripheral Artery Motion and Vascular Resistance With a Multimodal Wearable Sensor Under Pressure Perturbations

The status of peripheral arteries is known to be a key physiological indicator of the body's response to both acute and chronic medical conditions. In this paper, peripheral artery deformation is tracked by wearable photoplethysmograph (PPG) and piezo-electric (polyvinylidene difluoride, PVDF)...

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Published inJournal of biomechanical engineering Vol. 144; no. 8
Main Authors Wang, Lu, Ansari, Sardar, Cai, Yingjie, McCracken, Brendan, Hakam Tiba, M, Ward, Kevin R, Najarian, Kayvan, Oldham, Kenn R
Format Journal Article
LanguageEnglish
Published United States 01.08.2022
Subjects
Animals
Arteries
Hemodynamics
Humans
Photoplethysmography - methods
Swine
Vascular Resistance
Wearable Electronic Devices
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Summary:The status of peripheral arteries is known to be a key physiological indicator of the body's response to both acute and chronic medical conditions. In this paper, peripheral artery deformation is tracked by wearable photoplethysmograph (PPG) and piezo-electric (polyvinylidene difluoride, PVDF) sensors, under pressure-varying cuff. A simple mechanical model for the local artery and intervening tissue captures broad features present in the PPG and PVDF signals on multiple swine subjects, with respect to varying cuff pressure. These behaviors provide insight into the robustness of cardiovascular property identification by noninvasive wearable sensing. This is found to help refine noninvasive blood pressure measurements and estimation of systemic vascular resistance (SVR) using selected features of sensor amplitude versus applied pressure.
ISSN:1528-8951
DOI:10.1115/1.4053399