Reliability of Clinical Criteria for the Diagnosis of Dementia: A Longitudinal Multicenter Study

• The reliability of the clinical diagnosis of dementia was estimated by comparing the diagnosis made at 1-year intervals on 55 consecutive subjects with suspected cognitive impairment seen at three different centers by neurologists and gerontologists. The diagnosis was based on history and clinical...

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Published inArchives of neurology (Chicago) Vol. 46; no. 6; pp. 646 - 648
Main Authors Forette, Françoise, Henry, Jean François, Orgogozo, Jean Marc, Dartigues, Jean François, Péré, Jean Jacques, Hugonot, Lawrence, Israel, Liliane, Loria, Yvonne, Goulley, Françoise, Lallemand, Anne, Boller, François
Format Journal Article
LanguageEnglish
Published Chicago, IL American Medical Association 01.06.1989
Subjects
Aged
Aged, 80 and over
Biological and medical sciences
Clinical Trials as Topic
Dementia - diagnosis
Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes
Female
Follow-Up Studies
Geriatrics - methods
Humans
Longitudinal Studies
Male
Medical sciences
Mental Status Schedule
Middle Aged
Nervous system (semeiology, syndromes)
Neurology
Human
Validity
Nervous system diseases
Cognitive disorder
Follow up study
Multicenter study
Higher nervous function
Clinical investigation
Psychiatry
Dementia
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Summary:• The reliability of the clinical diagnosis of dementia was estimated by comparing the diagnosis made at 1-year intervals on 55 consecutive subjects with suspected cognitive impairment seen at three different centers by neurologists and gerontologists. The diagnosis was based on history and clinical examination, the criteria of the Diagnostic and Statistical Manual of Mental Disorders (revised ed 3), the Modified lschemic Score, and a computed tomographic scan. Fifty-two of 55 subjects were given the same diagnosis a year later indicating a reliability of 95%. The study shows that a diagnosis of dementia established by simple clinical criteria comparable to the NINCDS/ADRDA criteria affords sufficient reliability to allow the comparability of groups at different centers for purposes of research, including research on the evaluation of the efficacy of pharmacologic treatment.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ISSN:0003-9942
1538-3687
DOI:10.1001/archneur.1989.00520420066024