Manganese-Catalyzed C(α)-Alkylation of Oxindoles with Secondary Alcohols via Borrowing Hydrogen
A general and efficient C(α)-alkylation of oxindoles with unactivated secondary alcohols as alkylating agents catalyzed by a newly developed NNN-Mn(II) complex is reported. Mechanistic studies illustrate that the importance of the NH moiety in the complex and M–L cooperation play very important ro...
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Published in | Organometallics Vol. 40; no. 6; pp. 627 - 634 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
WASHINGTON
American Chemical Society
22.03.2021
Amer Chemical Soc |
Subjects | |
Online Access | Get full text |
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Summary: | A general and efficient C(α)-alkylation of oxindoles with unactivated secondary alcohols as alkylating agents catalyzed by a newly developed NNN-Mn(II) complex is reported. Mechanistic studies illustrate that the importance of the NH moiety in the complex and M–L cooperation play very important roles during the catalytic transformation. |
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ISSN: | 0276-7333 1520-6041 |
DOI: | 10.1021/acs.organomet.1c00009 |