Transmetalation as Key Step in the Diastereo- and Enantioselective Synergistic Cu/Pd-Catalyzed Allylboration of Alkynes with Racemic Allylic Carbonates

Cu/Pd-catalyzed alkyne allylboration with racemic allylic carbonates proceeds with total inversion of configuration. Preliminary studies show that this synergistic catalysis can be used to perform a dynamic asymmetric allylic alkenylation that provides enantioenriched carboboration products.

Saved in:
Bibliographic Details
Published inOrganometallics Vol. 39; no. 5; pp. 740 - 745
Main Authors Mateos, Jaime, Fuentes-Vara, Noelia, Fra, Laura, Rivera-Chao, Eva, Vázquez-Galiñanes, Nuria, Chaves-Pouso, Andrea, Fañanás-Mastral, Martín
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 09.03.2020
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Physical Sciences
Science & Technology
NUCLEOPHILES
REAGENTS
CROSS-COUPLING REACTION
MECHANISM
ALLYLATION
METAL
ALKYLATIONS
RACEMIZATION
ARYLBORATION
DERIVATIVES
Online AccessGet full text

Cover

More Information
Summary:Cu/Pd-catalyzed alkyne allylboration with racemic allylic carbonates proceeds with total inversion of configuration. Preliminary studies show that this synergistic catalysis can be used to perform a dynamic asymmetric allylic alkenylation that provides enantioenriched carboboration products.
ISSN:0276-7333
1520-6041
DOI:10.1021/acs.organomet.0c00010