Sugar-Based Lipid Headgroups:  How Sticky Are They?

This paper reports the synthesis of a disulfide-based exchangeable glycophospholipid and establishes that this lipid mixes, ideally, with a shorter-chain, phospholipid analogue in cholesterol-rich fluid bilayers. These findings indicate that associative interactions between carbohydrate headgroups a...

Full description

Saved in:
Bibliographic Details
Published inLangmuir Vol. 18; no. 4; pp. 981 - 983
Main Authors Sugahara, Michihiro, Uragami, Maki, Tokutake, Nobuya, Yan, Xun, Regen, Steven L
Format Journal Article
LanguageEnglish
Published American Chemical Society 19.02.2002
Online AccessGet full text

Cover

More Information
Summary:This paper reports the synthesis of a disulfide-based exchangeable glycophospholipid and establishes that this lipid mixes, ideally, with a shorter-chain, phospholipid analogue in cholesterol-rich fluid bilayers. These findings indicate that associative interactions between carbohydrate headgroups are unlikely to provide a significant driving force for the clustering of glycolipids in biological membranes.
Bibliography:ark:/67375/TPS-1R1RJNQV-P
istex:758052B018D4C70D97070781301205D04152041F
ISSN:0743-7463
1520-5827
DOI:10.1021/la015722y