Total Synthesis of the Sesquiterpene (−)-Merrillianin

The first total synthesis of (−)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occur...

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Published inOrganic letters Vol. 26; no. 16; pp. 3327 - 3331
Main Authors Shiina, Isamu, Iizumi, Takashi, Taniguchi, Saori, Sugimoto, Masuhiro, Shimazaki, Takahisa, Yamai, Yu-suke, Ogawa, Go, Yamada, Tetsuro, Shinohara, Shojiro, Kageyama, Yosuke, Kuboki, Teppei, Suwa, Yuki, Yonekura, Keita, Ito, Keiichi, Toyoyama, Kiyotaka, Tateyama, Satoru, Mori, Takahiro, Murata, Takatsugu
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 26.04.2024
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
ALDOL REACTIONS
OLEFINS
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Abstract The first total synthesis of (−)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occurring (−)-1.
AbstractList The first total synthesis of (-)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occurring (-)-1.
The first total synthesis of (−)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occurring (−)-1.
The first total synthesis of (-)-merrillianin ( ), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occurring (-)- .
Author Ogawa, Go
Murata, Takatsugu
Yonekura, Keita
Toyoyama, Kiyotaka
Sugimoto, Masuhiro
Shimazaki, Takahisa
Yamada, Tetsuro
Iizumi, Takashi
Taniguchi, Saori
Shiina, Isamu
Tateyama, Satoru
Mori, Takahiro
Yamai, Yu-suke
Shinohara, Shojiro
Suwa, Yuki
Kageyama, Yosuke
Ito, Keiichi
Kuboki, Teppei
AuthorAffiliation Department of Applied Chemistry, Faculty of Science
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  surname: Shiina
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Snippet The first total synthesis of (−)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and...
The first total synthesis of (-)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and...
The first total synthesis of (-)-merrillianin ( ), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and...
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Chemistry, Organic
Physical Sciences
Science & Technology
Title Total Synthesis of the Sesquiterpene (−)-Merrillianin
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