Total Synthesis of the Sesquiterpene (−)-Merrillianin

The first total synthesis of (−)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occur...

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Published inOrganic letters Vol. 26; no. 16; pp. 3327 - 3331
Main Authors Shiina, Isamu, Iizumi, Takashi, Taniguchi, Saori, Sugimoto, Masuhiro, Shimazaki, Takahisa, Yamai, Yu-suke, Ogawa, Go, Yamada, Tetsuro, Shinohara, Shojiro, Kageyama, Yosuke, Kuboki, Teppei, Suwa, Yuki, Yonekura, Keita, Ito, Keiichi, Toyoyama, Kiyotaka, Tateyama, Satoru, Mori, Takahiro, Murata, Takatsugu
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 26.04.2024
Amer Chemical Soc
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Summary:The first total synthesis of (−)-merrillianin (1), which is a natural sesquiterpene with a tricyclic structure having a cyclopentane ring and five- and seven-membered lactone parts, is demonstrated. This asymmetric total synthesis enabled the absolute stereostructure determination of naturally occurring (−)-1.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.3c03877