Visible-Light-Initiated Decarboxylative Alkylation of Quinoxalin-2(1H)‑ones with Phenyliodine(III) Dicarboxylates in Recyclable Ruthenium(II) Catalytic System

A efficient and sustainable approach for the synthesis of 3-alkylquinoxalin-2­(1H)-ones has been developed through visible-light-mediated decarboxylative alkylation of quinoxalin-2­(1H)-ones with phenyliodine­(III) dicarboxylates. This photocatalytic alkylation reaction could be conducted at ambient...

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Published inACS sustainable chemistry & engineering Vol. 7; no. 16; pp. 14153 - 14160
Main Authors Xie, Long-Yong, Jiang, Li-Lin, Tan, Jia-Xi, Wang, Yi, Xu, Xiang-Qin, Zhang, Bo, Cao, Zhong, He, Wei-Min
Format Journal Article
LanguageEnglish
Published American Chemical Society 19.08.2019
Subjects
Quinoxalin-2(1H)-ones
PEG 200
Recyclability
Alkylation
Visible-light catalysis
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Summary:A efficient and sustainable approach for the synthesis of 3-alkylquinoxalin-2­(1H)-ones has been developed through visible-light-mediated decarboxylative alkylation of quinoxalin-2­(1H)-ones with phenyliodine­(III) dicarboxylates. This photocatalytic alkylation reaction could be conducted at ambient temperature by employing eco-friendly PEG-200 as the reaction medium. Various 3-alkylquinoxalin-2­(1H)-ones were easily obtained through the present ruthenium­(II) catalytic system, which could be successfully recycled five times without the significant decrease of its efficiency.
ISSN:2168-0485
2168-0485
DOI:10.1021/acssuschemeng.9b02822