Duplex-Specific Nuclease-Enabled Target Recycling on Semiconducting Metal–Organic Framework Heterojunctions for Energy-Transfer-Based Organic Photoelectrochemical Transistor miRNA Biosensing

• Published in: Analytical chemistry (Washington) Vol. 94; no. 45; pp. 15856 - 15863
• Main Authors: Gao, Ge, Chen, Jia-Hao, Li, Cheng-Jun, Wang, Cheng-Shuang, Hu, Jin, Zhou, Hong, Lin, Peng, Xu, Qin, Zhao, Wei-Wei
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 15.11.2022
• Subjects: Biomedical materials; Biosensing Techniques; Biosensors; Cadmium sulfide; Channel gating; Chemistry; Electrochemical Techniques; Endonucleases; Energy Transfer; Heterojunctions; Hybridization; Limit of Detection; Medical innovations; Metal Nanoparticles; Metal-Organic Frameworks; MicroRNAs; MicroRNAs - genetics; miRNA; Nuclease; Polystyrene resins; Quantum Dots; Recycling; Ribonucleic acid; RNA; Semiconductor devices; Styrene; Transistors

Semiconductor metal–organic frameworks (MOFs) and heterojunctions have gained increasing attention in many fields, yet their full potential remains largely unexplored. Advanced optobioelectronics are envisioned to create more opportunities for innovative biomedical applications. This study reports a...