A Combinatorial Approach to [1,5]Benzothiazepine Derivatives as Potential Antibacterial Agents

[1,5]Benzothiazepines are widely used in a number of different therapeutic areas and therefore represent an interesting scaffold for de novo exploration. Recent literature reports suggest their value as antibacterial agents. The present paper reports the exploration of this scaffold for the generati...

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Published inJournal of combinatorial chemistry Vol. 3; no. 2; pp. 224 - 228
Main Authors Micheli, Fabrizio, Degiorgis, Fabio, Feriani, Aldo, Paio, Alfredo, Pozzan, Alfonso, Zarantonello, Paola, Seneci, Pierfausto
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 01.03.2001
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Applied
Chemistry, Medicinal
Chemistry, Multidisciplinary
Life Sciences & Biomedicine
Pharmacology & Pharmacy
Physical Sciences
Science & Technology
LIBRARIES
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Summary:[1,5]Benzothiazepines are widely used in a number of different therapeutic areas and therefore represent an interesting scaffold for de novo exploration. Recent literature reports suggest their value as antibacterial agents. The present paper reports the exploration of this scaffold for the generation of combinatorial libraries both in solution and on solid phase.
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ISSN:1520-4766
1520-4774
DOI:10.1021/cc0000949