Neurologic Manifestations of Leishmania spp. Infection

When listing common clinical signs of the spectra of Leishmania-derived diseases, neurologic malfunctions are not commonly included. Despite this, there are multiple reported instances both in human and veterinary medicine where neurologic manifestations, whether central or peripheral, are described...

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Bibliographic Details
Published inJournal of Neuroparasitology Vol. 2; pp. 20 - 24
Main Authors Petersen, Christine Anne, Greenlee, M Heather West
Format Journal Article
LanguageEnglish
Published Belgium Ashdin Publishing 01.01.2011
Subjects
Leishmania
CNS
macrophage
leishmaniasis
neurologic
ocular
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Summary:When listing common clinical signs of the spectra of Leishmania-derived diseases, neurologic malfunctions are not commonly included. Despite this, there are multiple reported instances both in human and veterinary medicine where neurologic manifestations, whether central or peripheral, are described. In this review, we describe neurologic manifestations seen during infection with Leishmania spp. with some discussion of the implicit effect of inflammation on the blood brain barrier in both medical and veterinary cases. Taken together, the material discussed here suggests that in patients from Leishmania-endemic areas, when observing neurologic symptoms, causation secondary to infection with Leishmania spp. should be highly considered.
Bibliography:ObjectType-Article-1
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ISSN:2090-2344
2090-2352
DOI:10.4303/jnp/N110401