Pregnancy complicated by thrombotic thrombocytopenic purpura with fetal sparing

Thrombotic thrombocytopenic purpura (TTP) occurred in a young woman during the ninth month of an uneventful pregnancy. At birth, the infant was asymptomatic, with a platelet count of 160,000/cu mm. Repeated examinations of the infant's peripheral blood film have shown normal platelet estimates...

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Bibliographic Details
Published inArchives of internal medicine (1960) Vol. 143; no. 11; p. 2207
Main Authors Blakowski, S A, Zacharski, L R, Telfer, M C
Format Journal Article
LanguageEnglish
Published United States 01.11.1983
Subjects
Adult
Female
Fetal Diseases - physiopathology
Humans
Platelet Aggregation
Pregnancy
Purpura, Thrombotic Thrombocytopenic - physiopathology
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Summary:Thrombotic thrombocytopenic purpura (TTP) occurred in a young woman during the ninth month of an uneventful pregnancy. At birth, the infant was asymptomatic, with a platelet count of 160,000/cu mm. Repeated examinations of the infant's peripheral blood film have shown normal platelet estimates and no fragmented erythrocytes. These findings support the conclusion that the placenta serves as an effective barrier to plasmatic changes presumed to be of importance in the pathogenesis of TTP.
ISSN:0003-9926
DOI:10.1001/archinte.1983.00350110201044