Energetic Material Synthesis: Scale-up Using a Novel Modular Microflow Reactor Setup

• Published in: Organic process research & development Vol. 28; no. 5; pp. 1458 - 1463
• Main Authors: Karaghiosoff, Konstantin, Klapötke, Thomas M., Völkl, Maurus B. R.
• Format: Journal Article
• Language: English
• Published: American Chemical Society 17.05.2024
• Subjects: continuous flow; flow reactor; nitroguanidine; high corrosion; upscaling; silica coating; Energetic material

The advantages of microflow reactors have proven to be manifold, e.g., the excellent cooling ability, which allows performing exothermic reactions like nitrations safely. A critical point remains the transition from gram scale to industrial production. On an industrial scale, they are often designed...