Epiretinal and vitreous membranes. Comparative study of 56 cases

Five morphologically distinguishable cell types were observed in 56 epiretinal and vitreous membranes obtained surgically from eyes with various ocular diseases: (1) retinal pigment epithelial (RPE) cells that were evident only in association with retinal detachment, (2)(macrophages, (3) fibrocytes,...

Full description

Saved in:
Bibliographic Details
Published inArchives of ophthalmology (1960) Vol. 99; no. 8; p. 1445
Main Authors Kampik, A, Kenyon, K R, Michels, R G, Green, W R, de la Cruz, Z C
Format Journal Article
LanguageEnglish
Published United States 01.08.1981
Subjects
Astrocytes - ultrastructure
Fibroblasts - ultrastructure
Humans
Macrophages - ultrastructure
Membranes - ultrastructure
Microscopy, Electron
Microscopy, Phase-Contrast
Pigment Epithelium of Eye - ultrastructure
Retina - ultrastructure
Retinal Diseases - pathology
Vitreous Body - ultrastructure
Online AccessGet more information

Cover

More Information
Summary:Five morphologically distinguishable cell types were observed in 56 epiretinal and vitreous membranes obtained surgically from eyes with various ocular diseases: (1) retinal pigment epithelial (RPE) cells that were evident only in association with retinal detachment, (2)(macrophages, (3) fibrocytes, (4) fibrous astrocytes that were characteristic of all disease groups, and (5) myofibroblast-like cells that had mostly the characteristics of fibrocytes and, occasionally, of RPE cells or fibrous astrocytes. The combination of cell types varied in different types of epiretinal membranes, but the formation of collagen and the development of cells with myofibroblast-like properties were common features and seemed to be within the capacity of several cell types. These two common features seem to be the basis for the contractile properties of epiretinal and vitreous membranes.
ISSN:0003-9950
DOI:10.1001/archopht.1981.03930020319025