Nitrogen-Containing Lanthanide Metal–Organic Framework Nanostructure for Fluorescent Detection of Lamotrigine

The rational design and exploitation of fluorescent nanomaterials with excellent properties is of great significance for the detection of lamotrigine (LTG). Herein, a novel lanthanide metal–organic framework was prepared via the self-assembly of a Tb3+ ion and an H2DimTA ligand. The as-prepared mate...

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Published inACS applied nano materials Vol. 5; no. 7; pp. 8723 - 8729
Main Authors Sun, Xue-Chun, Zhu, Ming-Chang, Wu, Shuang-Yan, Zhang, Ying, Bai, Xiao-Jue
Format Journal Article
LanguageEnglish
Published American Chemical Society 22.07.2022
Subjects
lanthanide metal−organic frameworks
nanostructure
lamotrigine
specific recognition
fluorescence detection
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Summary:The rational design and exploitation of fluorescent nanomaterials with excellent properties is of great significance for the detection of lamotrigine (LTG). Herein, a novel lanthanide metal–organic framework was prepared via the self-assembly of a Tb3+ ion and an H2DimTA ligand. The as-prepared material exhibits a lamellar nanostructure with plenty of pyrazole nitrogen sites (specific recognition sites for LTG), which can directly act as fluorescence detectors toward LTG detection. Their outstanding performance with a low limit of detection (1.89 μM), superior anti-interference capability, rapid response, and excellent durability shows their great potential in the field of fluorescence detection.
ISSN:2574-0970
2574-0970
DOI:10.1021/acsanm.2c01975