Triamcinolone aerosol. Treatment of aspirin-hypersensitive asthmatic patients

The efficacy of triamcinolone acetonide aerosol in the management of asthma in six patients with aspirin hypersensitivity was evaluated during a one-year trial. Five patients were previously chronically dependent on systemic corticosteroids and had undergone unsuccessful trials with cromolyn sodium...

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Bibliographic Details
Published inJAMA : the journal of the American Medical Association Vol. 238; no. 20; p. 2174
Main Authors Pingleton, W W, Bone, R C, Kerby, G R, Ruth, W E
Format Journal Article
LanguageEnglish
Published United States 14.11.1977
Subjects
Aerosols
Aspirin - immunology
Asthma - drug therapy
Asthma - immunology
Asthma - physiopathology
Drug Hypersensitivity
Humans
Lung - physiopathology
Prednisone - therapeutic use
Triamcinolone Acetonide - administration & dosage
Triamcinolone Acetonide - therapeutic use
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Summary:The efficacy of triamcinolone acetonide aerosol in the management of asthma in six patients with aspirin hypersensitivity was evaluated during a one-year trial. Five patients were previously chronically dependent on systemic corticosteroids and had undergone unsuccessful trials with cromolyn sodium therapy. Substantial reduction in corticosteroid requirements was observed; in two patients, oral prednisone therapy was completely eliminated. Forced expiratory volume and flow were maintained at levels better than those recorded before triamcinolone therapy throughout the year of follow-up. No substantial side effects due to triamcinolone were observed.
ISSN:0098-7484
DOI:10.1001/jama.1977.03280210066027