Health effects of tropospheric ozone
Two major categories of ozone effects on the respiratory tract are considered: impairment in the mechanical functions of the lung, and structural injury or functional impairment of specific types of cells in the respiratory tract. Data from controlled studies done over the past decade suggest that o...
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| Published in | Environmental science & technology Vol. 23; no. 3; pp. 257 - 263 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
American Chemical Society
01.03.1989
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| Online Access | Get full text |
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| Summary: | Two major categories of ozone effects on the respiratory tract are considered: impairment in the mechanical functions of the lung, and structural injury or functional impairment of specific types of cells in the respiratory tract. Data from controlled studies done over the past decade suggest that ozone-induced lung impairment measured by changes in forced expiratory volume occur as an exponential function of ozone concentration, possibly as a non-linear function of ventilation, and possibly as a linear function of exposure. The results of studies of cellular and tissue effects in experimental animals can reasonably be extrapolated to humans. They reveal increases in collagen content and thickening of septa between alveoli in the centriacinar region of the lung. |
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| Bibliography: | istex:FBC255ABE7AF67B3189B7AA1F662069E5BFF0CC0 ark:/67375/TPS-JL23R0T9-1 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
| ISSN: | 0013-936X 1520-5851 |
| DOI: | 10.1021/es00180a002 |