Thiol-Ene Synthesis of Cationic Carbosilane Dendrons: a New Family of Synthons

A variety of neutral and cationic carbosilane dendrons containing a wide range of active groups, such as −N3, −OH, −NH2, and −SH, at the focal points were synthesized from carbosilane vinyl dendrons BrG n V m from generations 1–3 by substitution of the bromine atom at the focal point and functionali...

Full description

Saved in:
Bibliographic Details
Published inOrganometallics Vol. 32; no. 6; pp. 1789 - 1796
Main Authors Fuentes-Paniagua, Elena, Peña-González, Cornelia E, Galán, Marta, Gómez, Rafael, de la Mata, F. Javier, Sánchez-Nieves, Javier
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 25.03.2013
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Inorganic & Nuclear
Chemistry, Organic
Physical Sciences
Science & Technology
BIOCOMPATIBILITY
CATALYSIS
EFFECTIVE CARRIERS
DRUG-DELIVERY
CLICK CHEMISTRY
CONSTRUCTION
REACTIVITY
DENDRIMERS
SCAFFOLDS
STABILIZED GOLD NANOPARTICLES
Online AccessGet full text

Cover

More Information
Summary:A variety of neutral and cationic carbosilane dendrons containing a wide range of active groups, such as −N3, −OH, −NH2, and −SH, at the focal points were synthesized from carbosilane vinyl dendrons BrG n V m from generations 1–3 by substitution of the bromine atom at the focal point and functionalization of the vinyl groups via thiol-ene click chemistry with HS(CH2)2NMe2·HCl. These dendritic wedges were characterized by NMR, MS, and elemental analysis.
ISSN:0276-7333
1520-6041
DOI:10.1021/om301217g