Scale-Up of a Reformatsky Reaction to an Indenyl Butanoate

A safe process for the Reformatsky reaction of 5-methoxy-1-indanone and methyl 2-bromo butyrate giving an indenyl butanoate was developed. It was scaled-up from the lab to the pilot plant. The results from two campaigns on pilot-plant scale are presented.

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Bibliographic Details
Published inOrganic process research & development Vol. 9; no. 2; pp. 216 - 218
Main Authors Scherkenbeck, Thomas, Siegel, Konrad
Format Journal Article
LanguageEnglish
Published American Chemical Society 01.03.2005
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Summary:A safe process for the Reformatsky reaction of 5-methoxy-1-indanone and methyl 2-bromo butyrate giving an indenyl butanoate was developed. It was scaled-up from the lab to the pilot plant. The results from two campaigns on pilot-plant scale are presented.
ISSN:1083-6160
1520-586X
DOI:10.1021/op049778l