Mycophenolic acid for psoriasis

Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A double-blind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P less than .01). A long-term safety study showed the occurre...

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Bibliographic Details
Published inArchives of dermatology (1960) Vol. 113; no. 9; p. 1203
Main Authors Lynch, W S, Roenigk, Jr, H H
Format Journal Article
LanguageEnglish
Published United States 01.09.1977
Subjects
Adolescent
Adult
Aged
Breast Neoplasms - chemically induced
Carcinoma, Squamous Cell - chemically induced
Clinical Trials as Topic
Double-Blind Method
Epiglottis
Female
Humans
Laryngeal Neoplasms - chemically induced
Male
Middle Aged
Mycophenolic Acid - adverse effects
Mycophenolic Acid - pharmacology
Mycophenolic Acid - therapeutic use
Psoriasis - drug therapy
Virus Diseases - etiology
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Summary:Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A double-blind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P less than .01). A long-term safety study showed the occurrence of hematologic abnormalities, viral infections, and carcinoma. The position of mycophenolic acid in the therapeutic treatment of psoriasis must await the results of a multicenter cooperative study.
ISSN:0003-987X
DOI:10.1001/archderm.1977.01640090051004