Atropisomeric Derivatives of 2‘,6‘-Disubstituted (R)-11-Phenylaporphine:  Selective Serotonin 5-HT7 Receptor Antagonists

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 44; no. 9; pp. 1337 - 1340
Main Authors Linnanen, Tero, Brisander, Magnus, Unelius, Lena, Rosqvist, Susanne, Nordvall, Gunnar, Hacksell, Uli, Johansson, Anette M
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 26.04.2001
Amer Chemical Soc
Subjects
Biological and medical sciences
Chemistry, Medicinal
Life Sciences & Biomedicine
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology & Pharmacy
Pharmacology. Drug treatments
Science & Technology
Serotoninergic system
BINDING
CROSS-COUPLING REACTIONS
ENANTIOMERS
Rat
Nitrogen heterocycle
Rodentia
Benzene derivatives
Selectivity
Tetracyclic compound
Serotonine receptor
In vitro
Vertebrata
Mammalia
Atropoisomerism
Structure activity relation
Animal
Affinity
Aromatic compound
Antagonist
Chemical synthesis
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More Information
Bibliography:ark:/67375/TPS-G6B3DPFK-N
istex:E2127FDA9E777C4A2DAA575E71F02EC6C3E00AAA
ISSN:0022-2623
1520-4804
DOI:10.1021/jm0108505