2-Phenyl-4(5)-[[4-(pyrimidin-2- yl)piperazin-1-yl]methyl]imidazole. A Highly Selective Antagonist at Cloned Human D4 Receptors

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 40; no. 1; pp. 1 - 3
Main Authors Thurkauf, Andrew, Yuan, Jun, Chen, Xi, He, Xiao Shu, Wasley, Jan W. F, Hutchison, Alan, Woodruff, Kristine H, Meade, Robin, Hoffman, Diane C, Donovan, Hilary, Jones-Hertzog, Deborah K
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 03.01.1997
Subjects
Antipsychotic Agents - chemistry
Biological and medical sciences
Catecholaminergic system
Clozapine - analogs & derivatives
Clozapine - chemistry
Dopamine D2 Receptor Antagonists
Humans
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Receptors, Dopamine D4
Human
Imidazole derivatives
Structure activity relation
Psychotropic
Dopamine receptor
Benzene derivatives
Affinity
Selectivity
Antagonist
Piperazine derivatives
In vitro
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SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-2623
1520-4804
DOI:10.1021/jm960637m