Reduction of Cp2ZrCl2 with Mischmetall:  A New Method for Generating an Efficient “Cp2Zr” Equivalent

A “Cp2Zr” equivalent is generated under mild conditions (THF, room temperature) by reducing Cp2ZrCl2 with cheap and readily available mischmetall (an alloy of Ce, La, Nd, and Pr). Coupling reactions, including those of terminal alkynes, can efficiently be achieved by using this reagent.

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Bibliographic Details
Published inOrganic letters Vol. 8; no. 14; pp. 2945 - 2947
Main Authors Denhez, Clément, Médégan, Sédami, Hélion, Florence, Namy, Jean-Louis, Vasse, Jean-Luc, Szymoniak, Jan
Format Journal Article
LanguageEnglish
Published WASHINGTON American Chemical Society 06.07.2006
Amer Chemical Soc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
METAL-PROMOTED CYCLIZATION
INTRAMOLECULAR CYCLIZATION
ALKYNES
BICYCLIZATION
ZIRCONOCENE COMPLEXES
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Summary:A “Cp2Zr” equivalent is generated under mild conditions (THF, room temperature) by reducing Cp2ZrCl2 with cheap and readily available mischmetall (an alloy of Ce, La, Nd, and Pr). Coupling reactions, including those of terminal alkynes, can efficiently be achieved by using this reagent.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1523-7060
1523-7052
DOI:10.1021/ol060712f