(S)-N-tert-Butyl-3-(4-(2-methoxyphenyl)piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

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Bibliographic Details
Published inJournal of medicinal chemistry Vol. 36; no. 10; pp. 1509 - 1510
Main Authors Cliffe, Ian A, Brightwell, Christopher I, Fletcher, Allan, Forster, Elaine A, Mansell, Howard L, Reilly, Yvonne, Routledge, Carol, White, Alan C
Format Journal Article
LanguageEnglish
Published Washington, DC American Chemical Society 01.05.1993
Subjects
Animals
Binding Sites
Biological and medical sciences
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Piperazines - metabolism
Piperazines - pharmacology
Psycholeptics: tranquillizer, neuroleptic
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
Rats
Receptors, Serotonin - metabolism
Serotonin Antagonists
Stereoisomerism
Synapses - drug effects
Rat
Psychotropic
Rodentia
Central nervous system
In vitro
Postsynaptic
Vertebrata
Biological fixation
Mammalia
Tranquillizer
Animal
S1A receptor
Antagonist
Presynaptic
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Bibliography:ark:/67375/TPS-7BVL1K81-3
istex:FF3804417A3452987F5C04EB6F62A18CA3D143C9
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-2623
1520-4804
DOI:10.1021/jm00062a028