A Stereoselective Three-Component Reaction:  KAl(SO4)2·12H2O, an Efficient and Reusable Catalyst for the One-Pot Synthesis of cis-Isoquinolonic Acids

KAl(SO4)2·12H2O is found to catalyze efficiently the stereoselective one-pot three-component cyclocondensation of homophthalic anhydride, aldehydes, and amines under mild conditions to afford the corresponding cis-isoquinolonic acids in good yields.

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Bibliographic Details
Published inJournal of organic chemistry Vol. 70; no. 1; pp. 350 - 352
Main Authors Azizian, Javad, Mohammadi, Ali A, Karimi, Ali R, Mohammadizadeh, Mohammad R
Format Journal Article
LanguageEnglish
Published American Chemical Society 07.01.2005
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Summary:KAl(SO4)2·12H2O is found to catalyze efficiently the stereoselective one-pot three-component cyclocondensation of homophthalic anhydride, aldehydes, and amines under mild conditions to afford the corresponding cis-isoquinolonic acids in good yields.
Bibliography:ark:/67375/TPS-QWL10R9F-S
istex:7E9CEA57658969D39DEADEF8C48BD951DA8BC94B
ISSN:0022-3263
1520-6904
DOI:10.1021/jo049138g