Dithallium(III)-Containing 30-Tungsto-4-phosphate, [Tl2Na2(H2O)2(P2W15O56)2]16–: Synthesis, Structural Characterization, and Biological Studies

• Published in: Inorganic chemistry Vol. 57; no. 12; pp. 7168 - 7179
• Main Authors: Ayass, Wassim W, Fodor, Tamás, Farkas, Edit, Lin, Zhengguo, Qasim, Hafiz M, Bhattacharya, Saurav, Mougharbel, Ali S, Abdallah, Khaled, Ullrich, Matthias S, Zaib, Sumera, Iqbal, Jamshed, Harangi, Sándor, Szalontai, Gábor, Bányai, István, Zékány, László, Tóth, Imre, Kortz, Ulrich
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 18.06.2018
• ISSN: 0020-1669; 1520-510X
• DOI: 10.1021/acs.inorgchem.8b00878

Here we report on the synthesis and structural characterization of the dithallium­(III)-containing 30-tungsto-4-phosphate [Tl2Na2(H2O)2­{P2W15O56}2]16– (1) by a multitude of solid-state and solution techniques. Polyanion 1 comprises two octahedrally coordinated Tl3+ ions sandwiched between two trilacunary {P2W15} Wells–Dawson fragments and represents only the second structurally characterized, discrete thallium-containing polyoxometalate to date. The two outer positions of the central rhombus are occupied by sodium ions. The title polyanion is solution-stable as shown by 31P and 203/205Tl NMR. This was also supported by Tl NMR spectra simulations including several spin systems of isotopologues with half-spin nuclei (203Tl, 205Tl, 31P, 183W). 23Na NMR showed a time-averaged signal of the Na+ counter cations and the structurally bonded Na+ ions. 203/205Tl NMR spectra also showed a minor signal tentatively attributed to the trithallium-containing derivative [Tl3Na­(H2O)2­(P2W15O56)2]14–, which could also be identified in the solid state by single-crystal X-ray diffraction. The bioactivity of polyanion 1 was also tested against bacteria and Leishmania.