Propofol anesthesia in a patient with Isaacs syndrome--report of a case and literature review

Isaacs syndrome is an unusual lower motor neuron disease characterized by myokymia (muscle twitching), muscular stiffness, and decreased tendon reflexes. We reported a patient who was affected with this rare disease, with manifestation of involuntary muscular contractions and required general anesth...

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Bibliographic Details
Published inActa anaesthesiologica Sinica Vol. 35; no. 4; p. 241
Main Authors Shyr, M H, Ho, A C, Lin, C C, Hsu, K Y, Yang, C H, Chen, C H
Format Journal Article
LanguageEnglish
Published China (Republic : 1949- ) 01.12.1997
Subjects
Adult
Anesthesia, Intravenous - methods
Anesthetics, Intravenous - pharmacology
Fasciculation - complications
Humans
Male
Propofol - pharmacology
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Summary:Isaacs syndrome is an unusual lower motor neuron disease characterized by myokymia (muscle twitching), muscular stiffness, and decreased tendon reflexes. We reported a patient who was affected with this rare disease, with manifestation of involuntary muscular contractions and required general anesthesia for bilateral tonsillectomies. Understanding the presentation and characterization of this unusual disease may be helpful in making choice of anesthetics or anesthetic techniques. Its possible mechanisms of action and its specific considerations in anesthesia in the literature are reviewed and discussed.
ISSN:0254-1319