The treatment of pulmonary edema in the absence of renal function. A role for sorbitol and furosemide

In doses sufficient to induce a rapid osmotic loss of fluid from the bowel, sorbitol can provide an alternate method of removing fluid in patients who lack renal function. Two patients with acute pulmonary edema and oliguric renal failure were treated with a combined therapy of sorbitol and furosemi...

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Bibliographic Details
Published inJAMA : the journal of the American Medical Association Vol. 241; no. 10; p. 1008
Main Authors Anderson, C C, Shahvari, M B, Zimmerman, J E
Format Journal Article
LanguageEnglish
Published United States 09.03.1979
Subjects
Acute Kidney Injury - complications
Acute Kidney Injury - physiopathology
Aged
Drug Therapy, Combination
Female
Furosemide - administration & dosage
Furosemide - pharmacology
Hemodynamics - drug effects
Humans
Male
Pulmonary Edema - complications
Pulmonary Edema - drug therapy
Pulmonary Edema - physiopathology
Sorbitol - administration & dosage
Sorbitol - pharmacology
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Summary:In doses sufficient to induce a rapid osmotic loss of fluid from the bowel, sorbitol can provide an alternate method of removing fluid in patients who lack renal function. Two patients with acute pulmonary edema and oliguric renal failure were treated with a combined therapy of sorbitol and furosemide. Their clinical, hemodynamic, and metabolic responses were strikingly similar to those achieved with furosemide therapy alone in patients with normal renal function.
ISSN:0098-7484
DOI:10.1001/jama.1979.03290360024020