Sesquiterpenoids and Norsesquiterpenoids from the Formosan Soft Coral Lemnalia l aevis
Eight new nornardosinane sequiterpenoids, laevinols A−H (1−8), a new neolemnane sesquiterpenoid, laevinone A (9), and the previously known 6β-acetyl-4β,5β-dimethyl-1(10)α-epoxy-2β-hydroxy-7-oxodecalin (10) and 11,12-dihydroxy-6,10-eremophiladiene (11) were isolated from the methylene chloride solubl...
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Published in | Journal of natural products (Washington, D.C.) Vol. 68; no. 12; pp. 1749 - 1753 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
American Chemical Society
26.12.2005
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Online Access | Get full text |
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Summary: | Eight new nornardosinane sequiterpenoids, laevinols A−H (1−8), a new neolemnane sesquiterpenoid, laevinone A (9), and the previously known 6β-acetyl-4β,5β-dimethyl-1(10)α-epoxy-2β-hydroxy-7-oxodecalin (10) and 11,12-dihydroxy-6,10-eremophiladiene (11) were isolated from the methylene chloride solubles of the Formosan soft coral Lemnalia laevis. Their structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro. |
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ISSN: | 0163-3864 1520-6025 |
DOI: | 10.1021/np050326r |