Sesquiterpenoids and Norsesquiterpenoids from the Formosan Soft Coral Lemnalia l aevis

Eight new nornardosinane sequiterpenoids, laevinols A−H (1−8), a new neolemnane sesquiterpenoid, laevinone A (9), and the previously known 6β-acetyl-4β,5β-dimethyl-1(10)α-epoxy-2β-hydroxy-7-oxodecalin (10) and 11,12-dihydroxy-6,10-eremophiladiene (11) were isolated from the methylene chloride solubl...

Full description

Saved in:
Bibliographic Details
Published inJournal of natural products (Washington, D.C.) Vol. 68; no. 12; pp. 1749 - 1753
Main Authors El-Gamal, Ali A. H, Chiu, E-Ping, Li, Chia-Hua, Cheng, Shi-Yie, Dai, Chang-Feng, Duh, Chang-Yih
Format Journal Article
LanguageEnglish
Published American Chemical Society 26.12.2005
Online AccessGet full text

Cover

Loading…
More Information
Summary:Eight new nornardosinane sequiterpenoids, laevinols A−H (1−8), a new neolemnane sesquiterpenoid, laevinone A (9), and the previously known 6β-acetyl-4β,5β-dimethyl-1(10)α-epoxy-2β-hydroxy-7-oxodecalin (10) and 11,12-dihydroxy-6,10-eremophiladiene (11) were isolated from the methylene chloride solubles of the Formosan soft coral Lemnalia laevis. Their structures were elucidated by extensive spectroscopic analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
ISSN:0163-3864
1520-6025
DOI:10.1021/np050326r