Abstract 13892: Purified Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats

• Published in: Circulation (New York, N.Y.) Vol. 140; no. Suppl_1 Suppl 1; p. A13892
• Main Authors: Melendez, Giselle C, Medina-Hernandez, Danielle, Pflum, Adam W, Xu, Vivian, Herrington, David M
• Format: Journal Article
• Language: English
• Published: by the American College of Cardiology Foundation and the American Heart Association, Inc 19.11.2019

IntroductionWe have previously shown that eicosapentaenoic acid (EPA) treatment decreases left ventricular (LV) diastolic dysfunction and interstitial cardiac fibrosis in rats with established hypertension. Evidence suggests that these beneficial effects may be related to the anti-inflammatory prope...