Abstract 13176: Beneficial Effects of Purified Eicosapentaenoic Acid on Myocardial Fibrosis and Diastolic Cardiac Function in Spontaneously Hypertensive Rats

• Published in: Circulation (New York, N.Y.) Vol. 138; no. Suppl_1 Suppl 1; p. A13176
• Main Authors: Pflum, Adam W, Robinson, Killian C, Bi, Jianli, Xu, Vivian, Herrington, David M, Meléndez, Giselle C
• Format: Journal Article
• Language: English
• Published: by the American College of Cardiology Foundation and the American Heart Association, Inc 06.11.2018

IntroductionHypertensive patients often experience left ventricular (LV) dysfunction associated with cardiac fibrosis. Pre-treatment with eicosapentaenoic acid (EPA) prevent these deleterious effects in animal models of acute pressure overload. We sought to determine whether purified EPA consumption...