LONGAMIDE AND 3,7-DIMETHYLISOGUANINE, 2 NOVEL ALKALOIDS FROM THE MARINE SPONGE AGELAS-LONGISSIMA

• Published in: Tetrahedron letters Vol. 36; no. 43; pp. 7893 - 7896
• Main Authors: CAFIERI, F, FATTORUSSO, E, MANGONI, A, TAGLIALATELASCAFATI, O
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier 23.10.1995
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology

A purine derivative, 3,7-dimethylisoguanine (1), and a novel alkaloid with the unusual pyrrolopiperazine nucleus, longamide (2), were isolated from the sponge Agelas longissima, and their structures established on the basis of spectroscopic data. In addition, 2 exhibited a mild antibacterial activit...