SYNTHESIS AND ANTIFUNGAL ACTIVITY OF NOVEL CATIONIC PNEUMOCANDIN B-O DERIVATIVES
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Published in | Journal of medicinal chemistry Vol. 37; no. 2; pp. 222 - 225 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
WASHINGTON
Amer Chemical Soc
21.01.1994
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Author | ABRUZZO, GK BARTIZAL, KF SCHMATZ, DM ZAMBIAS, RA MARRINAN, JA BALKOVEC, JM NOLLSTADT, KH KURTZ, MB DROPINSKI, JF MCFADDEN, DC BOUFFARD, FA HAMMOND, ML POWLES, MA |
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Keywords | LIPOPEPTIDE SYNTHESIS INHIBITORS ASPERGILLOSIS ECHINOCANDIN-B FUNGI PNEUMOCYSTIS-CARINII PNEUMONIA AMPHOTERICIN-B |
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PublicationTitle | Journal of medicinal chemistry |
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PublicationYear | 1994 |
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References | NICOLAU, DP (WOS:A1993KX91000001) 1993; 28 BEAULIEU, D (WOS:A1993KW34600002) 1993; 108 HAMMOND ML (WOS:A1994MT29200003.20) 1993 Polak, A (MEDLINE:1763183) 1991; 37 BRAJTBURG, J (WOS:A1992BV85L00006) 1992 MORRISON, VA (WOS:A1993KT89900002) 1993; 72 ARTYMOWICZ, RJ (WOS:A1993LN59300003) 1993; 12 BARTIZAL K (WOS:A1994MT29200003.5) 1993 BALKOVEC, JM (WOS:A1992GZ48400027) 1992; 35 PAYA, CV (WOS:A1993LA96300017) 1993; 16 RUIZHERRERA, J (WOS:A1991GL20800002) 1991; 60 HUDSON, AT (WOS:A1993KK18900014) 1993; 9 BARTIZAL, K (WOS:A1992JG14700013) 1992; 36 GALLIS, HA (WOS:A1990CW14300016) 1990; 12 REENTS, S (WOS:A1993KF91000015) 1993; 27 PURCELL KJ (WOS:A1994MT29200003.34) 1992; 14 LYMAN, CA (WOS:A1992JD53900003) 1992; 44 SYMONDS, WT (WOS:A1993KH28700001) 1993; 28 CLARK AM (WOS:A1994MT29200003.10) 1992 SCHMATZ, DM (WOS:A1990DR71400076) 1990; 87 BALKOVEC, JM (WOS:A1992JG83200003) 1992; 33 BRAJTBURG, J (WOS:A1990CQ72800001) 1990; 34 DENNING, DW (WOS:A1991FV09800011) 1991; 35 RICHARDSON, MD (WOS:A1991FY81300002) 1991; 28 YAMADA M (WOS:A1994MT29200003.50) 1990 HENSENS, OD (WOS:A1992KE50000007) 1992; 45 KITCHEN, VS (WOS:A1991FC11100016) 1991; 22 MEYER, RD (WOS:A1992HF38200023) 1992; 14 SCHMATZ, DM (WOS:A1992JM24700028) 1992; 36 TRABER, R (WOS:A1979GY99800035) 1979; 62 HUGHES, WT (WOS:A1992HW13700014) 1992; 116 Gordee, R. S. (CABI:19931214759) 1992 DOUGLAS C (WOS:A1994MT29200003.15) 1992 SCHMATZ, DM (WOS:A1992KE50000008) 1992; 45 CURRENT WL (WOS:A1994MT29200003.12) 1990 KELLERJUSLEN, C (WOS:A1976CJ89000011) 1976 TKACZ JS (WOS:A1994MT29200003.45) 1992 DOEBBELING BN (WOS:A1994MT29200003.14) 1990 WHITE, DJ (WOS:A1993KW72200007) 1993; 69 BENZ, F (WOS:A1974V124900016) 1974; 57 NOBLE, HM (WOS:A1991GZ10200020) 1991; 95 SCHWARTZ RE (WOS:A1994MT29200003.42) 1993 VOHRINGER, HF (WOS:A1993LB71100004) 1993; 24 TURNER WW (WOS:A1994MT29200003.47) 1993 Couroux, P. (CABI:19942025132) 1993; 59 DUBE, MP (WOS:A1993KW70500015) 1993; 6 RINALDI, MG (WOS:A1983SU07900008) 1983; 5 HECTOR, RF (WOS:A1993KG81400001) 1993; 6 GRAYBILL, JR (WOS:A1992HF38200025) 1992; 14 STELLBRINK, HJ (WOS:A1992JB68900025) 1992; 6 |
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S. – start-page: 2 year: 1992 ident: WOS:A1994MT29200003.10 publication-title: NEW APPROACHES ANTIF contributor: fullname: CLARK AM – volume: 14 start-page: S154 year: 1992 ident: WOS:A1992HF38200023 article-title: CURRENT ROLE OF THERAPY WITH AMPHOTERICIN-B publication-title: CLINICAL INFECTIOUS DISEASES contributor: fullname: MEYER, RD – volume: 45 start-page: 1886 year: 1992 ident: WOS:A1992KE50000008 article-title: PNEUMOCANDINS FROM ZALERION-ARBORICOLA .4. BIOLOGICAL EVALUATION OF NATURAL AND SEMISYNTHETIC PNEUMOCANDINS FOR ACTIVITY AGAINST PNEUMOCYSTIS-CARINII AND CANDIDA SPECIES publication-title: JOURNAL OF ANTIBIOTICS contributor: fullname: SCHMATZ, DM – volume: 108 start-page: 133 year: 1993 ident: WOS:A1993KW34600002 article-title: CORRELATION OF CILOFUNGIN INVIVO EFFICACY WITH ITS ACTIVITY AGAINST ASPERGILLUS-FUMIGATUS (1,3)-BETA-D-GLUCAN SYNTHASE publication-title: FEMS MICROBIOLOGY LETTERS contributor: fullname: BEAULIEU, D – volume: 14 start-page: 141 year: 1992 ident: WOS:A1994MT29200003.34 publication-title: CLIN INFECT DIS contributor: fullname: PURCELL KJ – year: 1993 ident: WOS:A1994MT29200003.47 publication-title: 205TH ACS NAT M DENV contributor: fullname: TURNER WW – volume: 62 start-page: 1252 year: 1979 ident: WOS:A1979GY99800035 article-title: CYCLOPEPTIDE ANTIBIOTICS FROM ASPERGILLUS SPECIES - STRUCTURE OF ECHINOCANDIN-C AND ECHINOCANDIN-D publication-title: HELVETICA CHIMICA ACTA contributor: fullname: TRABER, R – volume: 59 start-page: 179 year: 1993 ident: CABI:19942025132 article-title: Pneumocystis carinii: Once mistaken for a trypanosome, this peculiar pathogen is the leading cause of pneumonia in AIDS patients. publication-title: ASM News contributor: fullname: Couroux, P. – start-page: 375 year: 1993 ident: WOS:A1994MT29200003.42 publication-title: CUTANEOUS ANTIFUNGAL contributor: fullname: SCHWARTZ RE – volume: 36 start-page: 1648 year: 1992 ident: WOS:A1992JG14700013 article-title: INVITRO ANTIFUNGAL ACTIVITIES AND INVIVO EFFICACIES OF 1,3-BETA-D-GLUCAN SYNTHESIS INHIBITORS L-671,329, L-646,991, TETRAHYDROECHINOCANDIN-B, AND L-687,781, A PAPULACANDIN publication-title: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY contributor: fullname: BARTIZAL, K – volume: 28 start-page: 1 year: 1991 ident: WOS:A1991FY81300002 article-title: OPPORTUNISTIC AND PATHOGENIC FUNGI publication-title: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY contributor: fullname: RICHARDSON, MD – year: 1990 ident: WOS:A1994MT29200003.14 publication-title: 30TH P ICAAC ATL contributor: fullname: DOEBBELING BN – volume: 72 start-page: 78 year: 1993 ident: WOS:A1993KT89900002 article-title: THE SPECTRUM OF NON-CANDIDA FUNGAL-INFECTIONS FOLLOWING BONE-MARROW TRANSPLANTATION publication-title: MEDICINE contributor: fullname: MORRISON, VA – volume: 24 start-page: 388 year: 1993 ident: WOS:A1993LB71100004 article-title: PHARMACOKINETIC OPTIMIZATION IN THE TREATMENT OF PNEUMOCYSTIS-CARINII PNEUMONIA publication-title: CLINICAL PHARMACOKINETICS contributor: fullname: VOHRINGER, HF – start-page: 421 year: 1993 ident: WOS:A1994MT29200003.5 publication-title: CUTANEOUS ANTIFUNGAL contributor: fullname: BARTIZAL K – volume: 28 start-page: 341 year: 1993 ident: WOS:A1993KX91000001 article-title: FOCUS ON ATOVAQUONE - AN ALTERNATIVE TREATMENT FOR PNEUMOCYSTIS-CARINII PNEUMONIA publication-title: HOSPITAL FORMULARY contributor: fullname: NICOLAU, DP – volume: 37 start-page: 181 year: 1991 ident: MEDLINE:1763183 article-title: Antifungal chemotherapy--are we winning? publication-title: Progress in drug research. 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Progres des recherches pharmaceutiques contributor: fullname: Polak, A – volume: 35 start-page: 194 year: 1992 ident: WOS:A1992GZ48400027 article-title: SYNTHESIS, STABILITY, AND BIOLOGICAL EVALUATION OF WATER-SOLUBLE PRODRUGS OF A NEW ECHINOCANDIN LIPOPEPTIDE - DISCOVERY OF A POTENTIAL CLINICAL AGENT FOR THE TREATMENT OF SYSTEMIC CANDIDIASIS AND PNEUMOCYSTIS-CARINII PNEUMONIA (PCP) publication-title: JOURNAL OF MEDICINAL CHEMISTRY contributor: fullname: BALKOVEC, JM – year: 1990 ident: WOS:A1994MT29200003.12 publication-title: 30TH P ICAAC ATL contributor: fullname: CURRENT WL – volume: 6 start-page: 746 year: 1992 ident: WOS:A1992JB68900025 article-title: CANDIDA-KRUSEI SEPSIS IN HIV-INFECTION publication-title: AIDS contributor: fullname: STELLBRINK, HJ – volume: 27 start-page: 53 year: 1993 ident: WOS:A1993KF91000015 article-title: ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED HOSTS publication-title: ANNALS OF PHARMACOTHERAPY contributor: fullname: REENTS, S – start-page: 4147 year: 1976 ident: WOS:A1976CJ89000011 article-title: STRUCTURE OF CYCLOPEPTIDE ANTIBIOTIC, SL-7810 - ECHINOCANDIN-B publication-title: TETRAHEDRON LETTERS contributor: fullname: KELLERJUSLEN, C – start-page: 65 year: 1992 ident: WOS:A1992BV85L00006 article-title: AMPHOTERICIN-B - STUDIES FOCUSED ON IMPROVING ITS THERAPEUTIC EFFICACY publication-title: RECENT PROGRESS IN ANTIFUNGAL CHEMOTHERAPY contributor: fullname: BRAJTBURG, J – start-page: 421 year: 1993 ident: WOS:A1994MT29200003.20 publication-title: CUTANEOUS ANTIFUNGAL contributor: fullname: HAMMOND ML – year: 1992 ident: WOS:A1994MT29200003.15 publication-title: MAY AM SOC MICR NEW contributor: fullname: DOUGLAS C – volume: 33 start-page: 4529 year: 1992 ident: WOS:A1992JG83200003 article-title: REDUCTION STUDIES OF ANTIFUNGAL ECHINOCANDIN LIPOPEPTIDES - ONE-STEP CONVERSION OF ECHINOCANDIN-B TO ECHINOCANDIN-C publication-title: TETRAHEDRON LETTERS contributor: fullname: BALKOVEC, JM – volume: 44 start-page: 9 year: 1992 ident: WOS:A1992JD53900003 article-title: SYSTEMICALLY ADMINISTERED ANTIFUNGAL AGENTS - A REVIEW OF THEIR CLINICAL-PHARMACOLOGY AND THERAPEUTIC APPLICATIONS publication-title: DRUGS contributor: fullname: LYMAN, CA – volume: 14 start-page: S170 year: 1992 ident: WOS:A1992HF38200025 article-title: FUTURE-DIRECTIONS OF ANTIFUNGAL CHEMOTHERAPY publication-title: CLINICAL INFECTIOUS DISEASES contributor: fullname: GRAYBILL, JR – volume: 69 start-page: 112 year: 1993 ident: WOS:A1993KW72200007 article-title: MANAGEMENT OF PERSISTENT VULVO-VAGINAL CANDIDOSIS DUE TO AZOLE-RESISTANT CANDIDA-GLABRATA publication-title: GENITOURINARY MEDICINE contributor: fullname: WHITE, DJ – volume: 35 start-page: 1329 year: 1991 ident: WOS:A1991FV09800011 article-title: EFFICACY OF CILOFUNGIN ALONE AND IN COMBINATION WITH AMPHOTERICIN-B IN A MURINE MODEL OF DISSEMINATED ASPERGILLOSIS publication-title: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY contributor: fullname: DENNING, DW – start-page: 495 year: 1992 ident: WOS:A1994MT29200003.45 publication-title: EMERGING TARGETS ANT contributor: fullname: TKACZ JS – volume: 116 start-page: 953 year: 1992 ident: WOS:A1992HW13700014 article-title: A NEW DRUG (566C80) FOR THE TREATMENT OF PNEUMOCYSTIS-CARINII PNEUMONIA publication-title: ANNALS OF INTERNAL MEDICINE doi: 10.7326/0003-4819-116-11-953 contributor: fullname: HUGHES, WT – volume: 36 start-page: 1964 year: 1992 ident: WOS:A1992JM24700028 article-title: ANTIPNEUMOCYSTIS ACTIVITY OF WATER-SOLUBLE LIPOPEPTIDE L-693,989 IN RATS publication-title: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY contributor: fullname: SCHMATZ, DM – volume: 5 start-page: 1061 year: 1983 ident: WOS:A1983SU07900008 article-title: INVASIVE ASPERGILLOSIS publication-title: REVIEWS OF INFECTIOUS DISEASES contributor: fullname: RINALDI, MG – volume: 12 start-page: 563 year: 1993 ident: WOS:A1993LN59300003 article-title: ATOVAQUONE - A NEW ANTIPNEUMOCYSTIS AGENT publication-title: CLINICAL PHARMACY contributor: fullname: ARTYMOWICZ, RJ – volume: 9 start-page: 66 year: 1993 ident: WOS:A1993KK18900014 article-title: ATOVAQUONE - A NOVEL BROAD-SPECTRUM ANTIINFECTIVE DRUG publication-title: PARASITOLOGY TODAY contributor: fullname: HUDSON, AT – volume: 22 start-page: 204 year: 1991 ident: WOS:A1991FC11100016 article-title: CANDIDA-ALBICANS RESISTANCE IN AIDS publication-title: JOURNAL OF INFECTION contributor: fullname: KITCHEN, VS – volume: 57 start-page: 2459 year: 1974 ident: WOS:A1974V124900016 article-title: METABOLIC PRODUCTS OF MICROORGANISM .143. ECHINOCANDIN B, A NEW POLYPEPTIDE ANTIBIOTIC FROM ASPERGILLUS NIDULANS VAR ECHINULATUS - ISOLATION AND BUILDING UNITS publication-title: HELVETICA CHIMICA ACTA contributor: fullname: BENZ, F – volume: 34 start-page: 381 year: 1990 ident: WOS:A1990CQ72800001 article-title: AMPHOTERICIN-B - DELIVERY SYSTEMS publication-title: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY contributor: fullname: BRAJTBURG, J – volume: 45 start-page: 1875 year: 1992 ident: WOS:A1992KE50000007 article-title: PNEUMOCANDINS FROM ZALERION-ARBORICOLA .3. STRUCTURE ELUCIDATION publication-title: JOURNAL OF ANTIBIOTICS contributor: fullname: HENSENS, OD – volume: 6 start-page: 230 year: 1993 ident: WOS:A1993KW70500015 article-title: PREVENTION AND TREATMENT OF OPPORTUNISTIC INFECTIONS publication-title: CURRENT OPINION IN INFECTIOUS DISEASES contributor: fullname: DUBE, MP – volume: 95 start-page: 1439 year: 1991 ident: WOS:A1991GZ10200020 article-title: AN ECHINOCANDIN FROM AN ENDOPHYTIC CRYPTOSPORIOPSIS SP AND PEZICULA SP IN PINUS-SYLVESTRIS AND FAGUS-SYLVATICA publication-title: MYCOLOGICAL RESEARCH contributor: fullname: NOBLE, HM – volume: 12 start-page: 308 year: 1990 ident: WOS:A1990CW14300016 article-title: AMPHOTERICIN-B - 30 YEARS OF CLINICAL-EXPERIENCE publication-title: REVIEWS OF INFECTIOUS DISEASES contributor: fullname: GALLIS, HA – year: 1990 ident: WOS:A1994MT29200003.50 publication-title: AUG P INT C PAR PAR contributor: fullname: YAMADA M – volume: 6 start-page: 1 year: 1993 ident: WOS:A1993KG81400001 article-title: COMPOUNDS ACTIVE AGAINST CELL-WALLS OF MEDICALLY IMPORTANT FUNGI publication-title: CLINICAL MICROBIOLOGY REVIEWS contributor: fullname: HECTOR, RF – volume: 16 start-page: 677 year: 1993 ident: WOS:A1993LA96300017 article-title: FUNGAL-INFECTIONS IN SOLID-ORGAN TRANSPLANTATION publication-title: CLINICAL INFECTIOUS DISEASES contributor: fullname: PAYA, CV |
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Title | SYNTHESIS AND ANTIFUNGAL ACTIVITY OF NOVEL CATIONIC PNEUMOCANDIN B-O DERIVATIVES |
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