PRODUCTS FROM FURANS .7. A GENERAL-ROUTE FOR THE SYNTHESIS OF ALPHA-(1,2-CIS) AND BETA-(1,2-TRANS) GLYCOCONJUGATES VIA 1-O-ACYL AND 1-O-ETHOXYCARBONYL-2-AZIDO-2,3-DIDEOXYGLYCOPYRANOSIDES

• Published in: Journal of heterocyclic chemistry Vol. 28; no. 5; pp. 1325 - 1337
• Main Authors: GEORGIADIS, MP, COULADOUROS, EA
• Format: Journal Article
• Language: English
• Published: TAMPA HETERO CORPORATION 01.08.1991
• Subjects: Chemistry; Chemistry, Organic; Physical Sciences; Science & Technology; GLYCOSIDES; ACID; GLYCOPROTEINS; SUGARS; DERIVATIVES

A methodology for the synthesis of 2,3,6-trideoxy- and 2,3-dideoxy-2-aminoglycosides is presented. 2,3-Dideoxyhex-2-enopyranos-4-uloses (named also as 2H-pyran-3(6H)-Ones) were used for the synthesis of 1-O-acetyl, 1-O-ethyloxycarbonyl and 1-S-phenyl-2,3,6-trideoxy-(or 2,3-dideoxy)-2-azidoglycopyran...