PAMAM-guanylthiourea conjugates mask furin's substrate binding site: mechanistic insights from molecular docking and molecular dynamics studies assist the design of potential furin inhibitors
Furin, a subtilisin-like proprotein convertase human enzyme, is promising as a single therapeutic target for several viral manifestations. Hence, understanding the molecular mechanisms that are key to putative furin action would lead to the systemic development of specific and potent antivirals. To...
Saved in:
Published in | New journal of chemistry Vol. 47; no. 26; pp. 12468 - 12476 |
---|---|
Main Authors | , |
Format | Journal Article |
Language | English |
Published |
CAMBRIDGE
Royal Soc Chemistry
03.07.2023
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!