Supramolecular Dual Polypeptides Induced Tubulin Aggregation for Cancer Theranostics

• Published in: Journal of medicinal chemistry Vol. 65; no. 19; pp. 13473 - 13481
• Main Authors: Tang, Mian, Liu, Yao-Hua, Liu, Hua, Mao, Qiyue, Yu, Qilin, Kitagishi, Hiroaki, Zhang, Ying-Ming, Xiao, Lehui, Liu, Yu
• Format: Journal Article
• Language: English
• Published: WASHINGTON Amer Chemical Soc 13.10.2022
• Subjects: Chemistry, Medicinal; Life Sciences & Biomedicine; Pharmacology & Pharmacy; Science & Technology; NANOPARTICLES

The advent of macrocycle-based supramolecular chemistry can offer powerful strategies for regulating vital bioactivities in living systems and bring about emerging technology in biomedical science. Herein, we construct a suprabiomacromolecular nanosystem involving microtubules, cell-permeable porphy...