Mo(CO)(6) as a Solid CO Source in the Synthesis of Aryl/Heteroaryl Weinreb Amides under Microwave-Enhanced Condition

The facile transformation of aryl/heteroaryl nonaflates into corresponding amides via Pd-catalyzed aminocarbonylation using Mo(CO)(6) as a solid CO source under microwave-enhanced condition is reported. The method was found to be tolerant with respect to a diverse range of electronically biased aryl...

Full description

Saved in:
Bibliographic Details
Published inAustralian journal of chemistry Vol. 70; no. 1; pp. 44 - 51
Main Authors Ningegowda, Raghu, Bhaskaran, Savitha, Sajith, Ayyiliath M., Aswathanarayanappa, Chandrashekar, Padusha, M. Syed Ali, Shivananju, Nanjunda Swamy, Priya, Babu Shubha
Format Journal Article
LanguageEnglish
Published CLAYTON Csiro Publishing 01.01.2017
Subjects
Chemistry
Chemistry, Multidisciplinary
Physical Sciences
Science & Technology
IODIDES
CROSS-COUPLING REACTION
CARBON-MONOXIDE
SITU GENERATION
PALLADIUM-CATALYZED CARBONYLATION
BOND-FORMING REACTIONS
ARYL HALIDES
CONVENIENT
AMINOCARBONYLATION
BROMIDES
Online AccessGet full text

Cover

More Information
Summary:The facile transformation of aryl/heteroaryl nonaflates into corresponding amides via Pd-catalyzed aminocarbonylation using Mo(CO)(6) as a solid CO source under microwave-enhanced condition is reported. The method was found to be tolerant with respect to a diverse range of electronically biased aryl/heteroaryl nonaflates, and exceptional yields were obtained. The optimized protocol was further extended to a diverse range of amines.
ISSN:0004-9425
1445-0038
DOI:10.1071/CH16213