口服急性毒性试验中CrylC蛋白对鼠肠道菌群的影响
S8; 利用变性梯度凝胶电泳(DGGE)分析不同ICR(institute of cancer researcch)小鼠在口服急性毒性试验中摄入Cry1C蛋白前后其肠道菌群的变化,进而对该抗虫蛋白的食用安全性进行较为深入的研究.DGGE图谱经UPGAMA聚类分析显示:小鼠间菌群结构存在较明显的个体差异;实验期间,对照组小鼠灌胃前后其菌群基本保持稳定;实验组小鼠试验前后肠道菌群变化差异较对照组明显.随着灌胃的停止其变化差异在经历过高峰后会随着停喂时间的延长而减小,且菌相有逐渐恢复灌胃前结构的趋势.从肠道菌相的角度分析可知:该抗虫Cry1C蛋白对小鼠是基本安全的....
Saved in:
Published in | 农业生物技术学报 Vol. 18; no. 2; pp. 346 - 351 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | Chinese |
Published |
农业部转基因生物食用安全检验监督测试中心,北京,100083
2010
中国农业大学食品科学与营养工程学院,北京,100083%中国农业大学食品科学与营养工程学院,北京,100083 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | S8; 利用变性梯度凝胶电泳(DGGE)分析不同ICR(institute of cancer researcch)小鼠在口服急性毒性试验中摄入Cry1C蛋白前后其肠道菌群的变化,进而对该抗虫蛋白的食用安全性进行较为深入的研究.DGGE图谱经UPGAMA聚类分析显示:小鼠间菌群结构存在较明显的个体差异;实验期间,对照组小鼠灌胃前后其菌群基本保持稳定;实验组小鼠试验前后肠道菌群变化差异较对照组明显.随着灌胃的停止其变化差异在经历过高峰后会随着停喂时间的延长而减小,且菌相有逐渐恢复灌胃前结构的趋势.从肠道菌相的角度分析可知:该抗虫Cry1C蛋白对小鼠是基本安全的. |
---|---|
AbstractList | S8; 利用变性梯度凝胶电泳(DGGE)分析不同ICR(institute of cancer researcch)小鼠在口服急性毒性试验中摄入Cry1C蛋白前后其肠道菌群的变化,进而对该抗虫蛋白的食用安全性进行较为深入的研究.DGGE图谱经UPGAMA聚类分析显示:小鼠间菌群结构存在较明显的个体差异;实验期间,对照组小鼠灌胃前后其菌群基本保持稳定;实验组小鼠试验前后肠道菌群变化差异较对照组明显.随着灌胃的停止其变化差异在经历过高峰后会随着停喂时间的延长而减小,且菌相有逐渐恢复灌胃前结构的趋势.从肠道菌相的角度分析可知:该抗虫Cry1C蛋白对小鼠是基本安全的. |
Author | 郭星 许文涛 姚业成 曹思硕 罗云波 黄昆仑 |
AuthorAffiliation | 中国农业大学食品科学与营养工程学院,北京,100083%中国农业大学食品科学与营养工程学院,北京,100083;农业部转基因生物食用安全检验监督测试中心,北京,100083 |
AuthorAffiliation_xml | – name: 中国农业大学食品科学与营养工程学院,北京,100083%中国农业大学食品科学与营养工程学院,北京,100083;农业部转基因生物食用安全检验监督测试中心,北京,100083 |
Author_FL | Luo Yunbo Cao Sishuo Xu Wentao Guo Xing Yao Yecheng Huang Kunlun |
Author_FL_xml | – sequence: 1 fullname: Guo Xing – sequence: 2 fullname: Xu Wentao – sequence: 3 fullname: Yao Yecheng – sequence: 4 fullname: Cao Sishuo – sequence: 5 fullname: Luo Yunbo – sequence: 6 fullname: Huang Kunlun |
Author_xml | – sequence: 1 fullname: 郭星 – sequence: 2 fullname: 许文涛 – sequence: 3 fullname: 姚业成 – sequence: 4 fullname: 曹思硕 – sequence: 5 fullname: 罗云波 – sequence: 6 fullname: 黄昆仑 |
BookMark | eNrjYmDJy89LZWBQMTTQM7Y0s9TP0sssLs7TMzQzN9E1tzSz0DMyAEoZGAGRMQsDJ1ycg4G3uDgzycDAxMLM0tTMkpPB8Wn_4mdzep81LH3WsPzZ-klA8sX6qS9X9TzZsda5qDLH-cXs7ucz9z5dv_PlngUvmha8bJz8or_n-b4lz2e1PN278enkXh4G1rTEnOJUXijNzaDp5hri7KFbnpiXlpiXHp-VX1qUB5SJz6ssLs8qrkgCOc7ACOg0Y1LUAgBcKl0- |
ClassificationCodes | S8 |
ContentType | Journal Article |
Copyright | Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
Copyright_xml | – notice: Copyright © Wanfang Data Co. Ltd. All Rights Reserved. |
DBID | 2B. 4A8 92I 93N PSX TCJ |
DOI | 10.3969/j.issn.1674-7968.2010.02.023 |
DatabaseName | Wanfang Data Journals - Hong Kong WANFANG Data Centre Wanfang Data Journals 万方数据期刊 - 香港版 China Online Journals (COJ) China Online Journals (COJ) |
DatabaseTitleList | |
DeliveryMethod | fulltext_linktorsrc |
DocumentTitle_FL | Analysis of Intestinal Microbiota in Mice Fed with Cry1C Protein in Acute Oral Toxicity Test |
EndPage | 351 |
ExternalDocumentID | nyswjsxb201002023 |
GrantInformation_xml | – fundername: 国家自然科学基金; 转基因专项 funderid: (30800770); (2009ZX08011-001B和2008ZX08011-006) |
GroupedDBID | -04 2B. 2B~ 2C. 4A8 5XA 5XB 5XE 92G 92I 93N ACGFS ALMA_UNASSIGNED_HOLDINGS CCEZO CHDYS CW9 C~G DYU OZF PSX TCJ TGD U1G U5K |
ID | FETCH-wanfang_journals_nyswjsxb2010020233 |
ISSN | 1674-7968 |
IngestDate | Tue Feb 13 23:34:52 EST 2024 |
IsPeerReviewed | false |
IsScholarly | true |
Issue | 2 |
Keywords | Cry1C蛋白 变性梯度凝胶电泳 肠道菌群 转基因水稻 口服急性毒性 |
Language | Chinese |
LinkModel | OpenURL |
MergedId | FETCHMERGED-wanfang_journals_nyswjsxb2010020233 |
ParticipantIDs | wanfang_journals_nyswjsxb201002023 |
PublicationCentury | 2000 |
PublicationDate | 2010 |
PublicationDateYYYYMMDD | 2010-01-01 |
PublicationDate_xml | – year: 2010 text: 2010 |
PublicationDecade | 2010 |
PublicationTitle | 农业生物技术学报 |
PublicationTitle_FL | JOURNAL OF AGRICULTURAL BIOTECHNOLOGY |
PublicationYear | 2010 |
Publisher | 农业部转基因生物食用安全检验监督测试中心,北京,100083 中国农业大学食品科学与营养工程学院,北京,100083%中国农业大学食品科学与营养工程学院,北京,100083 |
Publisher_xml | – name: 农业部转基因生物食用安全检验监督测试中心,北京,100083 – name: 中国农业大学食品科学与营养工程学院,北京,100083%中国农业大学食品科学与营养工程学院,北京,100083 |
SSID | ssib004869569 ssj0000602725 ssib017478180 ssib051370055 |
Score | 3.6548321 |
Snippet | S8; 利用变性梯度凝胶电泳(DGGE)分析不同ICR(institute of cancer... |
SourceID | wanfang |
SourceType | Aggregation Database |
StartPage | 346 |
Title | 口服急性毒性试验中CrylC蛋白对鼠肠道菌群的影响 |
URI | https://d.wanfangdata.com.cn/periodical/nyswjsxb201002023 |
Volume | 18 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LaxRBEG6SCOJFFBXfBEkfPGzc6Z5H97HnRRD0lEA8hdnNriKygewGTU5RvJkQMHjwcQioCIIs3hSMv8Z9gT_CqprJzOAGjcIyFPXo_rqqd7q66Z5mbEY0axLvsK7UYEJbsZVlVZRsNiqNxEvsutdIdB3PDt-67c4t2DcXncWJyZ-lXUtrndpsfePQcyX_E1XgQVzxlOw_RDYvFBhAQ3zhCRGG55FizCOHq5gbySOX64CrEAlV5cY5IDwkTMy1KHEUcUBHc2O4Cnhkcx-YYbC6_iBAufa58nnkca25H2I9YOFrtPADbqqoowQRGpJRriVxYirM437EjU3mULyN5lCIbyEBmiosp8TUCIKfogATNLS5jpFQgFETdoPw04YCGIQUcuNmIuMcdB1CJFGIulBeXEigjRHWgRIwI-f4QPuFioMeQgw5GFAEolqooAE5gxyqQ4RpwAdOeQkl20aL3f2wFqYYFUIC15iAXAMuNkT45NlxL2iMdcoBEZo72CKQYhUOcVzUUdVScD0sUFtEhFlv8R0KcN4Tsg5AoYoRmyBIYK49khoEKQKL0unSUObiTludXlo0PtblSw7pwCWzheA0B5LpR4B_H16ldjUNr1jBbF5BtkFSwE8WaUW-2bO13n54v_2ohlowORFykh0T-FlGnMLcWShGD-XCZD1Pri282cEqRhfHkh5-MS5fQa26VeHRrco5kuNsJoN5408g6YBeq5m07pZyyflT7GQ2CZw26T_6NJvYuHeGmd7O2_6b7f7m-_7mh373OTyH3Rejj1s_vnyi_-Xw9bPBy_1e9-vo297wyd7o8e5wZ2vw_d3g1dPe_ufe7vZZdj2O5oO5SlbtUvYSaS-NOUeeY1OtlVbjPJtelqppuRresp6w63aS2DpxGlI7YlmLuhYX2LW_l3fxKEqX2Il0VwwuLV5mU53VtcYVSLY7tasUo18lQJ8r |
link.rule.ids | 315,783,787,4033,27937,27938,27939 |
linkProvider | CAB International |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=%E5%8F%A3%E6%9C%8D%E6%80%A5%E6%80%A7%E6%AF%92%E6%80%A7%E8%AF%95%E9%AA%8C%E4%B8%ADCrylC%E8%9B%8B%E7%99%BD%E5%AF%B9%E9%BC%A0%E8%82%A0%E9%81%93%E8%8F%8C%E7%BE%A4%E7%9A%84%E5%BD%B1%E5%93%8D&rft.jtitle=%E5%86%9C%E4%B8%9A%E7%94%9F%E7%89%A9%E6%8A%80%E6%9C%AF%E5%AD%A6%E6%8A%A5&rft.au=%E9%83%AD%E6%98%9F&rft.au=%E8%AE%B8%E6%96%87%E6%B6%9B&rft.au=%E5%A7%9A%E4%B8%9A%E6%88%90&rft.au=%E6%9B%B9%E6%80%9D%E7%A1%95&rft.date=2010&rft.pub=%E5%86%9C%E4%B8%9A%E9%83%A8%E8%BD%AC%E5%9F%BA%E5%9B%A0%E7%94%9F%E7%89%A9%E9%A3%9F%E7%94%A8%E5%AE%89%E5%85%A8%E6%A3%80%E9%AA%8C%E7%9B%91%E7%9D%A3%E6%B5%8B%E8%AF%95%E4%B8%AD%E5%BF%83%2C%E5%8C%97%E4%BA%AC%2C100083&rft.issn=1674-7968&rft.volume=18&rft.issue=2&rft.spage=346&rft.epage=351&rft_id=info:doi/10.3969%2Fj.issn.1674-7968.2010.02.023&rft.externalDocID=nyswjsxb201002023 |
thumbnail_s | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=http%3A%2F%2Fwww.wanfangdata.com.cn%2Fimages%2FPeriodicalImages%2Fnyswjsxb%2Fnyswjsxb.jpg |