窄带成像与白光在经尿道膀胱肿瘤切除术中的自身对照分析

R737.14; 目的:探讨窄带成像(narrow band imaging,NBI)辅助白光经尿道膀胱肿瘤切除术(transurethral resection of bladder tumor,TURBT)治疗膀胱尿路上皮癌的效果,总结NBI手术经验.方法:选择2018年4月至2020年1月北京大学第三医院泌尿外科就诊膀胱尿路上皮癌的患者,麻醉后行TURBT.术中先在白光下寻找膀胱肿瘤并切除,完整取出病理标本.换成NBI,寻找可疑病灶并切除,将病理标本完整取出.两组术后标本区分开分别送病理科,记录白光下病灶的数目、位置及病理诊断结果,同时记录NBI下白光残留病灶的情况.计算白光下电切后膀胱...

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Published in北京大学学报(医学版) Vol. 52; no. 4; pp. 697 - 700
Main Authors 邱敏, 徐楚潇, 王滨帅, 颜野, 邓绍晖, 肖春雷, 刘承, 卢剑, 田晓军, 马潞林
Format Journal Article
LanguageChinese
Published 北京大学第三医院泌尿外科,北京100191 2020
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Abstract R737.14; 目的:探讨窄带成像(narrow band imaging,NBI)辅助白光经尿道膀胱肿瘤切除术(transurethral resection of bladder tumor,TURBT)治疗膀胱尿路上皮癌的效果,总结NBI手术经验.方法:选择2018年4月至2020年1月北京大学第三医院泌尿外科就诊膀胱尿路上皮癌的患者,麻醉后行TURBT.术中先在白光下寻找膀胱肿瘤并切除,完整取出病理标本.换成NBI,寻找可疑病灶并切除,将病理标本完整取出.两组术后标本区分开分别送病理科,记录白光下病灶的数目、位置及病理诊断结果,同时记录NBI下白光残留病灶的情况.计算白光下电切后膀胱肿瘤残留的比例,评估NBI的效果.后期病例按时间顺序平均分为3组,统计各组的临床数据,观察NBI辅助白光下TURBT的学习曲线.结果:参加研究的患者共45例,其中男32例,女13例,年龄23 ~ 89岁,平均65.2岁.45例手术均顺利完成,术后未见明显并发症及发生.术中发现9例为单发,36例为多发,肿瘤最大径0.5 ~4.0 cm,平均2.2 cm.白光下切除标本病理诊断均为尿路上皮癌,另有19例白光切除后NBI辅助下再次切除标本病理诊断阳性(42.2%).按时间顺序将45例分为3组,每组15例,白光下切除后3组NBI的真阳性率分别为33.3%、46.7%、46.7%,假阳性率分别为60.0%、46.7%、26.7%.结论:TURBT是治疗膀胱尿路上皮癌的有效方式,NBI是白光的有效补充,能增加膀胱肿瘤的检出率,减少术后复发.NBI光源有一定的学习曲线,随着病例的增加,NBI下假阳性率逐渐降低,而术者NBI经验丰富后,在白光下对扁平样肿瘤的辨识度也逐渐提高,白光下肿瘤切除后NBI辅助治疗肿瘤残留率降低.
AbstractList R737.14; 目的:探讨窄带成像(narrow band imaging,NBI)辅助白光经尿道膀胱肿瘤切除术(transurethral resection of bladder tumor,TURBT)治疗膀胱尿路上皮癌的效果,总结NBI手术经验.方法:选择2018年4月至2020年1月北京大学第三医院泌尿外科就诊膀胱尿路上皮癌的患者,麻醉后行TURBT.术中先在白光下寻找膀胱肿瘤并切除,完整取出病理标本.换成NBI,寻找可疑病灶并切除,将病理标本完整取出.两组术后标本区分开分别送病理科,记录白光下病灶的数目、位置及病理诊断结果,同时记录NBI下白光残留病灶的情况.计算白光下电切后膀胱肿瘤残留的比例,评估NBI的效果.后期病例按时间顺序平均分为3组,统计各组的临床数据,观察NBI辅助白光下TURBT的学习曲线.结果:参加研究的患者共45例,其中男32例,女13例,年龄23 ~ 89岁,平均65.2岁.45例手术均顺利完成,术后未见明显并发症及发生.术中发现9例为单发,36例为多发,肿瘤最大径0.5 ~4.0 cm,平均2.2 cm.白光下切除标本病理诊断均为尿路上皮癌,另有19例白光切除后NBI辅助下再次切除标本病理诊断阳性(42.2%).按时间顺序将45例分为3组,每组15例,白光下切除后3组NBI的真阳性率分别为33.3%、46.7%、46.7%,假阳性率分别为60.0%、46.7%、26.7%.结论:TURBT是治疗膀胱尿路上皮癌的有效方式,NBI是白光的有效补充,能增加膀胱肿瘤的检出率,减少术后复发.NBI光源有一定的学习曲线,随着病例的增加,NBI下假阳性率逐渐降低,而术者NBI经验丰富后,在白光下对扁平样肿瘤的辨识度也逐渐提高,白光下肿瘤切除后NBI辅助治疗肿瘤残留率降低.
Author 颜野
邓绍晖
马潞林
卢剑
王滨帅
肖春雷
田晓军
刘承
徐楚潇
邱敏
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XU Chu-xiao
DENG Shao-hui
LIU Cheng
QIU Min
TIAN Xiao-jun
WANG Bin-shuai
LU Jian
MA Lu-lin
XIAO Chun-lei
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Keywords 膀胱肿瘤
经尿道膀胱肿瘤切除术
窄带成像
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Title 窄带成像与白光在经尿道膀胱肿瘤切除术中的自身对照分析
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