Luminogen compounds and the use of the same for biosensing and cellular imaging

Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I)...

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Published 25.10.2016
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Abstract Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I) in use for detecting thiol groups in biomolecules. The detection method of the present subject matter not only has high thio-selectivity and sensitivity, but also is rapid, convenient and handy.
AbstractList Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I) in use for detecting thiol groups in biomolecules. The detection method of the present subject matter not only has high thio-selectivity and sensitivity, but also is rapid, convenient and handy.
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References Tang et al. (2014/0255696) 20140900
(61110036) 19860500
Tang (2008/0220407) 20080900
Van Der Eycken et al. (2010/0190658) 20100700
(61003066) 19860100
Kanaoka et al. (3891669) 19750600
(2008185364) 20080800
Vargeese et al. (6020206) 20000200
Tang et al. (2013/0266953) 20131000
Tang et al. (2013/0089889) 20130400
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Snippet Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for...
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Title Luminogen compounds and the use of the same for biosensing and cellular imaging
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